The lush and verdant island of Corfu lies in the Ionian Sea, midway between Greece and Italy. The island has a long and colorful history. First colonized by the city-state of Corinth, Corfu has been ruled by the Romans, the Venetians, the French and the English. Corfu Town boasts fortresses bearing the insignia of the Venetian Republic, an esplanade lavishly planted by the French during the Napoleonic Wars, and an English cricket pitch. The island also offers some of the finest coastal scenery in the entire Mediterranean.

Did the catastrophic volcanic eruption that ravaged Santorini circa 1600 B.C. destroy Crete’s ancient Minoan civilization – and give birth to the myth of Atlantis? In 1967, archaeologists on Santorini unearthed the remains of a Bronze Age city that may have been home to as many as 30,000 people. Whether the Lost Continent of Atlantis is rooted in myth or reality, an undisputed fact remains. The eruption created a caldera – and one of the most dramatic land and seascapes in the entire Mediterranean. On Santorini, whitewashed buildings cling to vertiginous cliffs that plunge to a turquoise sea. Part of the Cyclades Archipelago, the three-island group of Santorini, Thirasia and uninhabited Aspronisi present the traveler with unforgettable vistas.

The island has had a number of names throughout history – from Strongyle or “Round” to Thera in honor of an ancient hero. Santorini is more recent and stems from the island church dedicated to St. Irene – Santa Rini to foreign sailors.

From the port of Kusadasi on Turkey’s Anatolian Coast, one travels into the past. Nearby stand the ruins of ancient Ephesus, a major site of archeological excavation. The city was once a Roman provincial capital and trading center. Ephesus is also home to several of Christendom’s holiest sites. St. Paul preached at the Great Theater and the ruins of Ephesus’ Basilica cover the tomb of Christ’s most beloved disciple, St. John the Apostle.

In Kusadasi, whitewashed stone houses rise in tiers behind the market district. The palm-lined esplanade is the center of town life, with thousands of merchants offering wares to rival the Grand Bazaar in Istanbul.

Istanbul rises from the Bosphorus, a vision of minarets and domes sparkling in the light. The capital of vanished empires, Istanbul is a true crossroad, the only city on Earth to span two continents. This meeting place of Europe and Asia, of Christian and Muslim, is one of the great adventures a traveler encounters. Browse the stalls of the world’s largest bazaar, explore ancient mosques and churches, and gaze at the stunning jewels in the Topkapi Palace.

Istanbul has dominated the Straits of Bosphorus for 25 centuries. As Constantinople, capital of the Eastern Roman Empire, it was a metropolis of stunning splendor when the great cities of Europe were mere villages.

The past maintains a vibrant presence in the cradle of Western civilization. Atop the Acropolis, the serene Parthenon sails above the commotion of the modern city. The tragedies of Aeschylus, Sophocles, and Euripides were performed in the Theater of Dionysus at the foot of the Acropolis. On Pnyx Hill, citizens of a fledgling democracy gathered to cast their votes on Athens’ destiny. Then there is the hustle and bustle of the modern city, a metropolis of 4.5 million that spreads out from the foot of Mt. Lycabettus and across the plain. Packed with busy shops and lively tavernas, modern Athens is a colorful counterpoint to classical Greece.

Piraeus is the port city for Athens and has been Athens’ port of entry for over two millennia.

Thanks to its proximity to the mainland, Mykonos was one of the first Greek islands to become an international travel destination. During the late ’60s and early ’70s, Mykonos was famed as a haunt for the rich. The island’s nightlife – then and now – was a glittering whirl of colored lights, music, and parties. But there’s another side to Mykonos – the neighboring island of Delos. In classical mythology, Delos was the birthplace of Apollo and his twin sister Artemis. Travelers to Delos can stroll among the island’s vast ruins, which include three temples consecrated to the Sun God and the famed Lions Walk.

Mykonos town features hip boutiques, restaurants, jewelry stores, souvenirs, taverns and cafés. The island’s famed windmills are found just south of the waterfront.

Limassol, the second-largest city in Cyprus and the biggest port in the Mediterranean transit trade, is an important tourist and commercial hub. Flanking Akrotiri Bay on the island’s southern coast, the town sprawls between two ancient cities, Amathus and Kourion.

Ashdod produces textiles, cosmetics, and half the electrical power generated in Israel. Yet it is best known as the portal to the Holy Land.

According to Scripture, Ashdod was once home to giants. It was here that the Philistines brought the captured Ark, celebrating their victory over the Israelites. Today, the city itself is a giant of industry, surpassing Haifa as the largest port in Israel. More importantly, Ashdod is your gateway to Jerusalem. This city in the hills of Judea is sacred to three of the world’s great faiths. For Jews, the Western Wall – the sole surviving remnant of the Second Temple – embodies their cultural and religious identity. Christians walk the Via Dolorosa and observe the Stations of the Cross, renewing Christ’s sacrifice. For Moslems, the city is home to the third holiest shrine in all Islam. From a spot near the El-Aqsa Mosque, Muhammad ascended into Heaven to receive the teaching of Allah.

The nearby Lassithi Plateau is the highest inhabited plateau in all Greece. Nearby Mt. Dikti rises some 7,218 feet (2,200m) above sea level.

White-washed houses climb the slopes of this charming port on the Gulf of Mirabello. The small harbor is surrounded by restaurants, cafés, and shops prepared to dispense everything under the sun – from necessities to souvenirs. Aghios Nikolaos is also your gateway to the Minoan ruins at Knossos and to the famous windmills of the Lassithi Plateau.

Italy’s third-largest city, Naples is a bustling metropolis famed for it stately buildings, crowded streets, pizza – and notoriously bad traffic. However, this beautiful city is rich in centuries-old culture and customs. Naples is also your gateway to the Isle of Capri, the fabled Amalfi Coast and the ruins of Pompeii, buried in ash by the cataclysmic eruption of Mt. Vesuvius in 79 A.D.

Naples boasts an ideal location, with both the ruins of Roman cities and the stunning Amalfi Coast in easy reach.

Your gateway to the Eternal City, Civitavecchia has served as Rome’s seaport since the 13th century. The port has a long and venerable history. The emperor Trajan built a pleasure villa near the modern city, while Bernini and Michelangelo designed the harbor fortifications.

Yet the Eternal City eternally beckons. The ancient capital of the Western World and the center of Christianity for nearly 2,000 years, Rome provides an inexhaustible feast. Visit the ruins of the Forum, view the splendors of the Sistine Chapel, or climb the Spanish Steps, once the heart of Rome’s Bohemian Quarter.

Rome has been a magnet luring the world’s greatest artists, architects, and philosophers since the days of the Caesars.