Strasbourg is the capital city of the Grand Est region, formerly Alsace, in northeastern France. It’s also the formal seat of the European Parliament and sits near the German border, with culture and architecture blending German and French influences. Its Gothic Cathédrale Notre-Dame features daily shows from its astronomical clock and sweeping views of the Rhine River from partway up its 142m spire.

Rüdesheim am Rhein is a town in the Rhine Valley, Germany. It’s known for winemaking, especially of Riesling wines. In the center, Drosselgasse is a lane lined with shops, taverns and restaurants. Nearby, Siegfried’s Mechanical Music Cabinet is a museum of automated musical instruments. Medieval Brömserburg Castle is home to the Rheingau Wine Museum, exhibiting wine paraphernalia from ancient times to the present.

Mannheim is a city in southwest Germany, on the Rhine and Neckar rivers. The baroque 18th-century Mannheim Palace houses historical exhibits, plus the University of Mannheim. In the grid-like center, called the Quadrate, Marktplatz Square features a baroque fountain with statues. Planken shopping street leads southeast to the Romanesque Water Tower, in the art nouveau gardens of Friedrichsplatz.